![]() This variant has been reported in 90% of all cases in that country. Currently, more than 29 countries have detected this variant. The Lambda variant (C.37 or B 1.1.1) was detected as early as December 2020 in Lima, Peru. The mutation (K417N) acquired by the Delta Plus variant is not something new. The Delta Plus variant is resistant to antibody cocktails (artificially produced monoclonal antibodies), binds more tightly to the ACE2 receptor, thereby increasing transmissibility, exhibits resistance to COVID-19 drugs, and evades the immune response elicited by vaccinated individuals. Now, the “third wave” is expected to emerge from the Delta Plus variant ( B.1.617.2.1/AY.1) that has appeared across 12 countries, including India, UK, Poland, Switzerland, Portugal, Russia, Japan, Nepal, China, Canada, Turkey, and the US. Delta Plus, Lambda, and the third COVID wave The Delta variant is primarily responsible for the “second wave” in 98 countries. ![]() Now, following the Beta and Gamma variants, we have the Delta variant, which shows 60% more transmissibility than the Alpha variant. The Alpha variant, for instance, is 50% more transmissible than the original Wuhan strain. We’ve witnessed SARS-CoV-2 (the causative virus for COVID-19 disease) mutating rapidly and acquiring a constellation of mutations. ![]() However, some of them may evolve to become more infectious, or evade human antibody responses, a phenomenon called “convergent evolution”, observed in many past pandemics. With increased virus replication, we give the virus a higher chance for mutations to occur, hence the new variants.Ī majority of these new mutations are innocuous. The emergence of new RNA virus variants isn’t unusual, and coronaviruses are no different. ![]()
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